SAM e...S-Adenosyl Methionine

SAM-e has undergone dozens of trial involving thousands of patients. Researchers studying the healthful effects of SAM e have identified two different actions that may benefit the joints.

SAM-e increases the production of methyl-thioadenosine, an intermediate that reduces inflammation and which may partially account for the joint benefits of SAM e.
SAM-e support the production of healthy connective tissue through a process called transulfuration. In this process, critical components of connective tissue, including glucosamine and the chondroitin sulfates, are sulfated by SAM e metabolism. The metabolism of SAM e also results in the production of L-cysteine, an important amino acid used by the body to generate a family of sulfur-containing compounds of critical importance including glutathione. Some of these compounds are themselves the building blocks needed for the synthesis of cartilage, ligaments, tendons, and the bone matrix.

Not all SAM-e is of the active (S, S) form.> SAM e is a chiral molecule and therefore consists of two forms: (S,S) SAM e and (R,S) SAM e. The biologically active SAM e form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow Formulas® SAM e is made naturally by microbiological fermentation and then specially processed to preserve 68-80% (S,S) SAM e, the highest active level available. Pharmaceutical grade, stabilized SAM e 400 is a full 400 mg elemental SAM e from 800 mg of SAM e tosylate disulfate. SAM e 400 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.

>SAM e is an amino acid derivative that has been clinically proven to benefit brain, joint and liver function. It also contributes to energy production and longevity. Please click here for more information.

>Ingredients: Enteric Coated S-Adenosyl Methionine (from 800mg of SAM e tosylate disulfate), 400 mg each, 30 Tabs >Other Ingredients: Microcrystalline cellulose, enteric coating (methacrylate copolymers), glycerol behenate, magnesium silicate, triethyl citrate, glycerol palmitostearate, medium chain triglycerides, magnesium stearate, silicon dioxide, mannitol, sodium starch glycolate, titanium dioxide, and yellow iron oxide.

>Usage: Take 1 tablet per day on an empty stomach, or as directed by your qualified health consultant. Store in a cool, dry place. Suitable for vegetarians.

>WARNING: Individuals using prescribed medications such as antidepressants, including Serotonin Re-Uptake Inhibitors and MAO Inhibitors should consult a physician before using. Individuals with Parkinson's disease, bi-polar disorder or manic depression should not use SAM e. >

Natural Sam-e

SAM e 30 Tabs - 400 mg each - $39.95

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